The story takes off right where Bloodline ended. As Quincey Harker turns his back on his bloodline, he leaves his home at Castle Dracula and goes in search of Mary Seward. Mary has since fled back to her home of Purfleet and wants nothing to do with the darkside. But Mary soon realizes that she can't get away. Her father succombs to a strange virus where are his blood is taken from his body and soon, Mary's patients are dying from the same affliction as well. She knows that evil is near and when Harker comes to her asking for help, she has to decide whether Harker truely wants to turn his back on evil or whether he's toying with her emotions.